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"Object reference not set to an instance of an object."`

I received 3 xlsx files from a client.  I opened them without a problem, translated them, and, when I tried to save them as target, I get the error message "Object reference not set to an instance of an object."  I tried many solutions that Ì've seen here but none worked.

Finally I created a brand new Excel file with a single word:  Test.  Studio will not save it back to Excel after I translated it.

Can anyone please help me?

Tim