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SDL start-up error

Hello, I'm having some fundamental problems when I start up SDL. When I try to translate a single file, I see "One or more errors occurred." When I click on "OK," I thereafter see the TM and Document Settings screen, but I am no longer able to select among my many TMs. Critically, I am not able to see the Microsoft MT (yes, I was using it properly until a few days ago, with the appropriate API). Any help would be appreciated.